[Original Article] Impact of Major Side Branch on Periprocedural Enzyme Elevation and Long-Term Outcome in Patients Undergoing Percutaneous Coronary Intervention and Brachytherapy for In-Stent Restenosis

Impact of Major Side Branch on Periprocedural Enzyme Elevation and Long-Term Outcome in Patients Undergoing Percutaneous Coronary Intervention and Brachytherapy for In-Stent Restenosis

Am J Cardiol. 2004 Jun 1;93(11):1394-7, A9.

Pramod Kuchulakanti, MD, Seung-Woon Rha, MD, Lowell F. Satler, MD, William O. Suddath, MD, Augusto D. Pichard, MD, Kenneth M. Kent, MD, Rajbabu Pakala, PhD, Daniel A. Canos, MPH, Ellen E. Pinnow, MS, and Ron Waksman, MD

Side branch occlusion is 1 mechanism for the increase of creatine phosphokinase-MB after percutaneous coronary intervention and is associated with longterm adverse events. We studied 248 patients who underwent brachytherapy for in-stent restenosis with and without side branches, compared levels of creatine phosphokinase-MB with procedural, in-hospital, and long-term clinical outcomes, and found that patients with side branches have increased levels of creatine phosphokinase-MB after percutaneous coronary intervention and higher rates of restenosis, target vessel, and target lesion revascularization at 6-month follow-up. 2004 by Excerpta Medica, Inc.
(Am J Cardiol 2004;93:1394–1397)