THE IMPACT OF ANEMIA ON 6-MONTH ANGIOGRAPHIC AND 1-YEAR CLINICAL OUTCOMES IN ACUTE MYOCARDIAL INFARCTION PATIENTS UNDERGOING PERCUTANEOUS CORONARY INTERVENTION
- Chang Gyu Park, Dong Joo Oh, Cardiology Department, Eulji General Hospital, Seoul, South Korea, Cardiovascular Center, Korea University Guro Hospital, Seoul, South Korea
Background
The significance of anemia in patients (pts) with acute myocardial infarction (AMI) treated with percutaneous coronary intervention (PCI) remains controversial. The aim of this study was to evaluate the impact of anemia on the angiographic and clinical outcomes of AMI pts following successful PCI.
Methods
A total of 881 consecutive AMI pts treated with PCI between 2004 and 2010 were enrolled. Anemia was defined using WHO criteria (hemoglobin level <13 g/dL for men and <12 g/dL for women). The study population was divided into 2 groups: anemia group (n=349) and non-anemia group (n=532). 6-month angiographic and 1 year clinical outcomes were compared between the 2 groups.
Results
Baseline clinical characteristics showed that anemia group had more hypertension, diabetes and congestive heart failure. At 6months, angiographic outcomes were similar between the 2 groups. However, anemia group had higher incidence of in-hospital death than non-anemia group. Further, anemia group showed higher incidence of total death, cardiac death, TLR-MACEs and TVR-MACE up to 2 years than those of non anemia group (Table). Multivariate analysis showed anemia was an independent predictor of mortality at 2 years (Adjusted OR 3.78, CI 2.19-6.52, p<0.001).
- Table.
Six-month angiographic and 2-year clinical outcomes
Conclusion
In conclusion, anemia on admission in AMI pts treated with PCI was associated with higher mortality and MACEs up to 2 years, suggesting special care should be exercised when an AMI pt has anemia on admission.
Copyright © 2012 Published by Elsevier Inc. All rights reserved.
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