CLINICAL AND ANGIOGRAPHIC CHARACTERISTICS OF VASOSPASTIC ANGINA IN TEENAGERS

• Amro Elnagar, 
• Seung-Woon Rha, 
• Byoung Geol Choi, 
• sung il Im, 
• Sunwon Kim, 
• Jin Oh Na, 
• Seongwoo Han,
• Cheol Ung Choi, 
• Hong Euy Lim, 
• Jin Won Kim, 
• Eung Ju Kim, 
• Hong-Seog Seo, 
• Chang Gyu Park, 
• Dong Joo Oh

• Cardiovascular Center, Korea University Guro Hospital, Seoul, South Korea

Background

Coronary vasospasm is one of known causes for ischemic chest pain, however little data is available regarding its characteristics in teenagers as compared with those of elderly patients (pts).

Methods

A total 3034 consecutive pts underwent coronary angiography with acetylcholine (Ach) provocation test were enrolled for the study. Study population were divided into according to age into 2 groups (Up to 20 years: 36 pts & more than 20 years: 2998 pts). Significant CAS was defined as transient >70% luminal narrowing with chest pain and/or ST segment changes.

Results

Baseline characteristics were similar between the two groups except that teenagers group had more males (75% vs.47.7%, p = 0.001), while older group had more hypertension (47% vs.11.1%, p<0.001) & dyslipidemia (18.8% vs.0%,p = 0.004). After the adjustment of baseline differences, there was a trend toward higher incidence of ischemic chest pain in the elderly group during the Ach provocation test. However, other clinical & angiographic characteristics of Ach test were similar between the two groups (Table).

Conclusion

Even in teenagers, coronary vasospasm assessed by (Ach) provocation test showed similar clinical and angiographic parameters to elderly group during the test.

Copyright © 2012 Published by Elsevier Inc. All rights reserved.