Background

Although there are data comparing the individual drug-eluting stents (DES) in unprotected left main coronary artery (ULMCA) percutaneous coronary intervention (PCI), there is lack of data in overall comparison of first versus second generation DESs. In this present study we are intended to compare the first and second generation DESs in PCI for ULMCA.

Methods

A total 276 consecutive patients (pts) underwent PCI for ULMCA with DESs were enrolled for this study. Patients who received BMS (n=7) were excluded from the study. Study population was classified as two groups; Patients who received first generation DESs (n=189) and second generation DESs (n=87). We analysed 6 months angiographic and 1 year clinical outcomes between the two groups.

Results

Baseline clinical characteristics were comparable between the two groups. There was no significant difference in 6 month angiographic outcomes including follow up minimum luminal diameter (MLD), diameter stenosis (DS) and late lumen loss (LL) (p>0.05, Table 1) and 1 year clinical outcomes including mortality, repeat revascularization, stent thrombosis and major adverse cardiac events (MACE) between the two groups (p>0.05, Table 2).

Conclusion

In PCI for ULMCA, first generation and second generation DESs were comparable regarding 6-month angiographic and 1-year clinical outcomes in a series of Asian population.

Copyright © 2014 Published by Elsevier Inc.