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Background

It is little known as long-term clinical outcomes for coronary artery spasm.

Methods

A total 1118 patients (pts) undergoing coronary angiography with acetylcholine provocation test from Nov 2004 to Oct 2010 from prospective spasm registry of Cardiovascular Center of Korea University Guro Hospital were enrolled. The follow-up duration was 5-year. The definition of positive coronary spasm test was defined as coronary vasospasm of more than 70%. After propensity score matching, the patient number of both group was 421.

Results

After Propensity score matching, there was no difference in mortality, cardiac death, myocardial infarction except recurrent chest pain requiring repeat coronary angiography that had the higher incidence in positive CAS group (p=0.003) (Table). Also, in proportional hazard cox-regression analysis adjusted by co-variates such as age, gender, hypertension, diabetes, dyslipidemia, current smokers, current alcoholics, myocardial bridge, positive CAS was associated with the increase of incidence of recurrent chest pain (HR, 1.7; 95% CI, 1.012-2.612; p=0.022).

Conclusions

In our study, coronary artery spasm didn't increase the incidence of mortality, cardiac death, and myocardial death except recurrent chest pain during 5-year clinical follow-up period.

Copyright © 2014 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.